6/30/96


We are looking at large numbers of electron micrographs on which we want to

quantitate the number of gold particles. Does anyone know of any program

that can take an electron micrograph (or a scanned TIFF image of a

micrograph) and count the number of gold particles? If there is such a

program, can it be used to count gold particles of two different sizes?

Thanks,

Sanford Simon

Sanford M. Simon

Laboratory of Cellular Biophysics

Box 304

Rockefeller University

1230 York Avenue

New York, N.Y. 10021

212-327-8130 (voice)

212-327-8022 (fax)

simon@rockvax.rockefeller.edu (e-mail)


NIH Image (Mac Version) by Wayne Rasband would be IMHO ideal for you. It

will count the particles in a field of view as well give you their relative sizes (areas).

Documentation is excellent and also available. NIH Image is public domain and free.

You can download by FTP a copy from the following sites:

zippy.nimh.nih.gov (site maintained by NIH & best place to look for current info)

www.amc.anl.gov (site maintained by Nestor for Microscopy & Microanalysis

usually a version behind but accessible)

log into either specifying a user name of

anonymous

and a password of

youremailaddress@yourhostcomputerdomain

at either site you will have to search the directory structure to find the

right place but it will be obvious.

on Zippy look under /pub/nih-image

on Nestor look under

/ANLSoftwareLibrary/4-MacShareware/Imaging/NIH-Image & SpinOffs

The current version is 1.60.

Nestor

Your Friendly Neighborhood SysOp

zaluzec@Sparc5.Microscopy.Com


Under DOS/Windows, "analySIS" connects to Philips, and possibly other,

TEMs and has functions for evaluating images of immunogold labelled

sections. It is sold by Soft Imaging Software, Gmbh, Germany, att.

Vasant Desai, Tel +49 251 798 000, Fax +49 251 798 00 99.

SIS just announced a website at http://www.soft-imaging-web.de

Finn-Mogens Haug

University of Oslo, Inst.bas.med.sci.

Department of anatomy E-mail: f.m.haug@basalmed.uio.no

Box 1105 Blindern Phone : +47 22 85 12 67

N-0317 Oslo, NORWAY Fax : +47 22 85 12 78


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