2/20/97




Hi

Has anyone used Green Fluorescent Protein? I would like to use it for determining cell proliferation (because of the experimental set up, it is difficult to measure cell population directly).

Also, does anyone know of any dyes that do not affect cell viability but also will be retained by the cell long term (~2-3 weeks) without being metabolized or compartmentalized?

Eric Johnston

ericdj@seas.upenn.edu


Eric,

Molecular Probes has a great web site - http://www.probes.com that you may

find helpful or call them for technical help at 541-465-8353 if you don't

have access to the www.

Beth Richardson

EM Lab Coordinator

Botany Department

University of Georgia

Athens, GA 30602

Phone - (706) 542-1790

FAX - (706) 542-1805

Email - beth@dogwood.botany.uga.edu


GFP is good, but it knocks out most of the green dyes, if you want to

double label anything, since it has a broad spectra. PKH from sigma is

another choice for tagging, etc., but I think that goes only to 10 days.

Good luck.

Rachel Teitelbaum

teitelba@aecom.yu.edu


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