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Phase Genomics Seminar

March 5 @ 12:00 PM - 1:00 PM

Join us on March 5th for a seminar with ICBR Bioinformatics and Phase Genomics in CGRC 133

Event Title: How Hi-C is transforming genome and metagenome assembly

Event Description: Chromosome conformation capture methods like Hi-C measure the 3D organization of DNA in vivo using a combination of crosslinking, proximity-ligation, and paired-end sequencing.

Because this method captures genomic contiguity on intact chromosomes, the resultant information can be used to generate end-to-end chromosome-scale scaffolds for large genomes.  Since Hi-C junctions form within intact cells, any sequences interacting by Hi-C must have originated from the same species/strain in a mixed population, enabling metagenomic deconvolution.

Capturing genomic proximity information in vivo removes several major obstacles in genome and metagenome assembly, improving the quality and efficiency of genome discovery efforts.

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March 5
12:00 PM - 1:00 PM


(352) 273-8030


CGRC Room 133
2033 Mowry Road
Gainesville, FL 32610 United States
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