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Phase Genomics Seminar

March 5 @ 12:00 PM - 1:00 PM

Join us on March 5th for a seminar with ICBR Bioinformatics and Phase Genomics in CGRC 133

Event Title: How Hi-C is transforming genome and metagenome assembly

Event Description: Chromosome conformation capture methods like Hi-C measure the 3D organization of DNA in vivo using a combination of crosslinking, proximity-ligation, and paired-end sequencing.

Because this method captures genomic contiguity on intact chromosomes, the resultant information can be used to generate end-to-end chromosome-scale scaffolds for large genomes.  Since Hi-C junctions form within intact cells, any sequences interacting by Hi-C must have originated from the same species/strain in a mixed population, enabling metagenomic deconvolution.

Capturing genomic proximity information in vivo removes several major obstacles in genome and metagenome assembly, improving the quality and efficiency of genome discovery efforts.

Registration is Closed

Details

Date:
March 5
Time:
12:00 PM - 1:00 PM

Organizer

ICBR
Phone:
(352) 273-8030
Email:
ICBR-ContactUs@ad.ufl.edu
Website:
www.biotech.ufl.edu

Venue

CGRC Room 133
2033 Mowry Road
Gainesville, FL 32610 United States
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