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Proteomics Research Seminar
April 1 @ 11:45 AM - 1:30 PM
Speaker : Dr. Subhra Chakraborty
Join us on April 1st as Dr. Subhra Chakraborty (Professor, Fellow of Indian National Academy of Sciences, National Institute of Plant Genome Research, Aruna Asaf Ali Marg, New Delhi-110067, India) comes to ICBR to discuss nutritional quality and agricultural productivity as it relates to sustainable food production worldwide.
Nutritional quality and agricultural productivity are the two key issues to the sustainable food production worldwide. While compositions of nutrients in the storage organs greatly influence the organ development and determine the nutritive quality, patho-stress is a major impediment during post-harvest storage and plant productivity. Nutrient- and immune-response in plant are complex phenomena and the exact physiological relevance and functional modification caused as a result of nutrient and/or anti-nutrient accumulation and disease is poorly understood. Cellular response is modulated by cross-talks of diverse pathways mediated by many genes and proteins and understanding their language may uncover various signaling networks that control and regulate a multitude of biological and physiological processes. To better understand the regulatory networks and metabolic pathways involved in increased protein synthesis and reserve accumulation and decrease in anti-nutrient in plants, we have developed comparative proteomes of wild-type and genetically modified crops using proteo-metabolomics approach. Next to determine the cellular circuitry that operates in plant immunity during plant-fungal interaction, we have applied a system approach to analyze comparative organ-specific transcriptome and sub-cellular proteomes in food crops. Network modeling based on our datasets illustrates immune responsive regulatory hubs and functional modules towards species-specific adaptation for cell survival, while the comparative analyses of tuber and fruit proteomes uncover potential regulators of nutrient response. These findings will not only impact plant biology, but in near future would be useful for identifying biomarkers, prioritize molecular targets, and pathway bioengineering for hardier and nutrient rich crops.