Dr. Steve Goodison: Curriculum Vitae (July, 2005)
Higher Education
- 1993
- PhD. University of Oxford, UK
Thesis entitled: The transcriptional regulation of the insulin gene
- 1989
- B.Sc. First Class Honors in Biochemistry
Swansea University, UK
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Present Position
- 2003-present
- Associate Professor (tenure-track)
Department of Surgery
University of Florida, Shands Health Science Center
653 West 8th Street
Jacksonville FL 32209
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Previous Positions
- 2001-2003
- Assistant Adjunct Professor
Dept. of Pathology and UCSD Cancer Center, San Diego, CA
- 1997-2001
- Dept. of Pathology and UCSD Cancer Center,
University of California, San Diego CA, USA
- 1995-1997
- Senior Research Fellow
Cancer Diagnosis and Metastasis Research Laboratory
University of Oxford, UK
- 1992-1995
- Wellcome Trust Prize Fellow
Department of Clinical Biochemistry
University of Oxford, UK
- 1994
- Wellcome Trust Visiting Fellow
(with Professor Richard Goodman, Institute Director)
Vollum Institute of Advanced Medical Sciences
Oregon Health Sciences University, Portland, Oregon, USA
- 1994
- Royal Society Travelling Fellow
Department of Physiology
University of Sao Paulo, Brazil
- 1989-1992
- Wellcome Trust Prize Scholar
Department of Clinical Biochemistry
University of Oxford, UK
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Awards and Prizes
- 2003
- Graduate of National Center for Leadership in Academic Medicine
- 2001-2003
- UCSD Cancer Center Special Recruit in Molecular Pathology
- 1999-2001
- Sidney Kimmel Scholar Award for Cancer Research
- 1995
- FEBS Research Fellowship (Federation of European Biochemical Societies)
- 1993
- Royal Society Travelling Fellowship
- 1994
- Wellcome Trust Visiting Fellowship
- 1992-1994
- Wellcome Trust Prize Research Fellowship
- 1989-1993
- Domus Scholarship, Linacre College (University of Oxford)
- 1989-1993
- Wellcome Trust Prize Scholarship (for PhD. studies)
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Grants and Contracts Obtained
| 2004-2009 |
NIH RO1 5CA108597 |
Identification and functional analysis of breast tumor metastasis genes. |
$1,250,000 |
| Role : Principal Investigator |
| 2006-2008 |
Susan Komen Foundation |
Isolation of metastatsis-inhibiting monoclonal antibodies. |
$250,000 |
| Role : Principal Investigator |
| 2005-2008 |
Florida Biomedical Program |
Genomic analysis of voided urine to detect bladder cancer. |
$470,000 |
| Role : Co-Principal Investigator / Mentor |
| 2004-2008 |
NIH K08 DK06137 |
CAR and adenoviral gene therapy for diabetic renal disease. |
$375,000 |
| Role : Co-Sponsor/mentor |
| 2000-2002 |
California Cancer Research Program |
Detection of bladder cancer by quantitative telomerase monitoring. |
$220,000 |
| Role : Principal Investigator |
| 1999-2001 |
Sidney Kimmel Cancer Foundation Scholar Award |
Characterization of the hTERT promoter. |
$200,000 |
| Role : Principal Investigator |
| 2000-2004 |
National Institutes of Health (UO1) |
Molecular Characterization of Prostate Cancer. |
$6,100,000 |
| Role : Co-Investigator |
| 2000-2004 |
National Institutes of Health (R21/R33) |
Cancer Classification Based on Alternatively Spliced mRNA Isoforms. |
$2,300,000 |
| Role : Co-Investigator |
| 2001-2004 |
National Institutes of Health (P20) |
In Vivo Cellular and Molecular Imaging. |
$1,600,000 |
| Role : Co-Investigator |
| 2001-2003 |
Chugai BioPharmaceuticals |
Metastases related gene discovery program. |
$550,000 |
| Role : Co-Principal Investigator |
| 2002-2003 |
American Cancer Society Pilot Project Grant |
Studies on the transcriptional regulation of telomerase components during cellular transformation. |
$40,000 |
| Role : Principal Investigator |
| 1996-1997 |
Oxford Health Services District Research Council |
CD44 promoter analysis |
$120,000 |
| Role : Co-Investigator |
| 1995-1998 |
Boehringer Mannheim Contract |
Breast cancer gene discovery program. |
$330,000 |
| Role : Co-Principal Investigator |
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Research Leadership
Conception, Direction and Supervision of the following Projects:
- Management of Cancer Center Core resources: Set up and manage fluorescent microscopy suite, including Spectral Imaging system (UCSD).
Setting up of a Molecular Pathology core service (San Diego and UF).
Member of Laboratory Design Team for new UCSD Cancer Center building (San Diego).
Planning and design of Shands/UF laboratories.
- Metastasis-related gene discovery effort resulting in the derivation of a unique isogenic breast metastasis model and the subsequent identification of several candidates now under genetic manipulation and functional analysis.
Personnel: 5-7
- Transcriptional regulation, analysis of the promoters of several genes, including telomerase subunits, CD44, and insulin.
Personnel: 2-3
- Cytogenetic analyses for identification of tumor cell-specific chromosomal aberrations.
Personnel: 2
- Function of novel isoforms of the hTERT telomerase gene.
Personnel: 2
- Molecular profiling projects on breast and prostate tumor tissues using microarray and proteomic technologies.
Personnel: 2-3
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Recruitment
- Recruited research scientists and technicians from junior to senior scientist level.
- Served on numerous clinical and research faculty recruitment committees and interview boards for UCSD and UF Colleges of Medicine.
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Teaching
- Lectures and tutorials teaching Cancer-related subjects and Biochemistry to Medical Students at Oxford University, UK (1993-1996).
- Laboratory training of several graduate students and post-doctoral research staff.
- Lectures and tutorials for science and medical graduates at UCSD and UF 1998 - present.
- Senior mentor for clinical staff (UF academic mentoring program) 2003-present
- Mentorship/training for faculty, postdoctoral and medical residents at UCSD and UF.
- Training and supervision of graduate and postgraduate students at UCSD.
- Resident teaching courses in Molecular Biology and Molecular Diagnostics at UF.
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Professional Affiliations
- 1992-1997
- Biochemical Society
- 1996-present
- American Association of Cancer Research (AACR)
- 2003-present
- Association of Clinical Scientists
- 2004-present
- Metastasis Research Society
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Peer Review Activities
Review Panel activity
| DOD USAMRMC Breast Cancer Program Review Panel |
2006 - |
Susan Komen Foundation Review Panel |
2005, 2006 - |
Review of articles for the multiple scientific journals including:
| Journal of the National Cancer institute (JNCI) |
Oncogene |
| Cancer Research |
Journal of Pathology |
| Clinical Cancer Research |
Journal of Clinical Pathology |
| American Journal of Pathology |
Biotechniques |
| Lancet |
Neoplasia |
| Invasion and Metastasis |
Cancer Gene Therapy |
| Biochemical Journal |
Gene |
| etc....... |
Grant applications reviewed for the following funding bodies:
- American Cancer Society, UCSD Cancer Center, Biotechnology and Biological Sciences Research Council (BBSRC) (UK), Medical Research Council (UK), Dutch Cancer Society, Israeli Cancer Society, various British Cancer Societies, Oxford University Faculty Board and Oxford Health Authority.
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Academic and Scientific Referees
- Professor James Feramisco
Dept. of Medicine, UCSD
9500 Gilman Drive
La Jolla, CA 92093-0612 USA
- Professor Webster Cavenee
Director, Ludwig Institute for Cancer Research
9500 Gilman Drive
La Jolla, CA 92093-0658 USA
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